Information for healthcare professionals on blood clotting following COVID-19 va

[Argirios Argiriou]

07/05/2021

Information for healthcare professionals on blood clotting following COVID-19 vaccination

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11. Signs and symptoms
While the detailed case review is ongoing, it is important to ensure all health professionals are alert to relevant symptoms which require further clinical review and investigation. Advise patients to seek urgent medical advice if they experience any of the following symptoms more than 4 days and within 28 days of coronavirus vaccination:

new onset of severe headache, which is getting worse and does not respond to simple painkillers
an unusual headache which seems worse when lying down or bending over, or may be accompanied by blurred vision, nausea and vomiting, difficulty with speech, weakness, drowsiness or seizures
new unexplained pinprick bruising or bleeding
shortness of breath, chest pain, leg swelling or persistent abdominal pain
If you have clinical concerns, patients should be urgently referred to hospital and to appropriate specialist services for further assessment, particularly if the symptoms are unexplained and present in combination with thrombocytopaenia. Further guidance for secondary care is available with specific guidance produced for Emergency Departments and Acute Medical Units and primary care.

Mild flu-like symptoms, including headache, chills and fever remain one of the most common side effects of any COVID-19 vaccine. These generally appear within a few hours and resolve within a day or two.

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[Argirios Argiriou]

10/05/2021

Guidance produced by the Expert Haematology Panel (EHP) focussed on Vaccine induced Thrombosis and Thrombocytopenia (VITT)

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[Argirios Argiriou]

22/05/2021

Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology

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