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Direct Oral Anticoagulants and Coronary Artery Disease

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Argirios Argiriou:
Originally Published 17 March 2022
Arteriosclerosis, Thrombosis, and Vascular Biology
Volume 42, Number 5
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Highlights
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The benefits of direct oral anticoagulants in patients with coronary artery disease without an indication for oral anticoagulation are still debated.
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The combination of direct oral anticoagulants and antiplatelet medications can increase the bleeding risk in patients and a thorough risk and benefit assessment needs to be considered.
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In patients with atrial fibrillation and stable coronary artery disease, newer guidelines recommend continuation of direct oral anticoagulants without the addition of an antiplatelet agent.
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Other novel anticoagulants which have inherently lower bleeding risks while retaining ischemic benefits may soon become available.

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