No benefit from antibiotics in acute uncomplicated diverticulitis!

[Argirios Argiriou]

No benefit from antibiotics in acute uncomplicated diverticulitis
The AVOD study (Br J Surg. 2012 Apr; 99(4):532-9) was a multicentre randomized study performed to investigate the need of antibiotic treatment in acute uncomplicated diverticulitis. Six hundred and twenty-three patients were randomized to treatment with (314 patients) or without (309 patients) antibiotics. Complications were found in six patients (1.9%) in the no antibiotic and three (1.0%) in the antibiotic group (p=0.302). The median hospital stay was three days in both groups. Recurrent diverticulitis follow-up was similar in both groups (16%, p=0.895). We conclude that antibiotic treatment for acute uncomplicated diverticulitis neither accelerated recovery nor prevented complications or recurrence. Based on the results, antibiotics should therefore be reserved mainly for the treatment of complicated diverticulitis.

Abbas Chabok,  Kenneth Smedh

Correspondence:  Abbas Chabok,  Kolorektalsektionen, Kirurgkliniken, Västmanlands sjukhus SE-721 89 Västerås, Sweden

abbas.chabok@ltv.se

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