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Use of placebo controls in the evaluation of surgery: systematic review.

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Argirios Argiriou:
BMJ 2014; 348 doi: Δεν είναι ορατοί οι σύνδεσμοι (links). Εγγραφή ή Είσοδος (Published 21 May 2014)

What this study adds

    In many of the reviewed trials improvement was present in both arms suggesting that the clinical effect may not be a result of the surgery; moreover, statistical superiority of the surgical procedure over the placebo was small

    The absence of an observational or non-treatment control group in most studies precludes any evaluation of the magnitude of the placebo effect

    Placebo controlled surgical trials are not free from adverse events, but the harms can be minimised and the placebo arm is generally much safer than the surgery arm

    Placebo controlled trials of surgery are a powerful, feasible way of showing the efficacy of surgical procedures and without them ineffective treatment may continue unchallenged


Δεν είναι ορατοί οι σύνδεσμοι (links). Εγγραφή ή Είσοδος

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