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Αντιυπερτασική αγωγή σε ασθενείς ενδιάμεσου καρδιαγγειακού κινδύνου;

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Argirios Argiriou:
N Engl J Med 2016; 374:2009-2020May 26, 2016DOI: 10.1056/NEJMoa1600175

Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease

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Conclusions

Therapy with candesartan at a dose of 16 mg per day plus hydrochlorothiazide at a dose of 12.5 mg per day was not associated with a lower rate of major cardiovascular events than placebo among persons at intermediate risk who did not have cardiovascular disease. (Funded by the Canadian Institutes of Health Research and AstraZeneca; ClinicalTrials.gov number, NCT00468923.)

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