Forum Πρωτοβάθμιας Φροντίδας Υγείας
ΠΦΥ -Εκπαίδευση => Αποσπάσματα από τον έντυπο & ηλεκτρονικό τύπο => Μήνυμα ξεκίνησε από: Argirios Argiriou στις 5 Ιουνίου 2014, 22:51:12
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BMJ 2014; 348 doi: http://dx.doi.org/10.1136/bmj.g3253 (Published 21 May 2014)
What this study adds
In many of the reviewed trials improvement was present in both arms suggesting that the clinical effect may not be a result of the surgery; moreover, statistical superiority of the surgical procedure over the placebo was small
The absence of an observational or non-treatment control group in most studies precludes any evaluation of the magnitude of the placebo effect
Placebo controlled surgical trials are not free from adverse events, but the harms can be minimised and the placebo arm is generally much safer than the surgery arm
Placebo controlled trials of surgery are a powerful, feasible way of showing the efficacy of surgical procedures and without them ineffective treatment may continue unchallenged
http://www.bmj.com/content/348/bmj.g3253